盛静逸

工作及教育经历

2020.09-2023.08东南大学 生物科学与医学工程学院 副研究员

2016.11-2019.04香港中文大学医学院 内科与药物治疗系 博士后

2012.04-2016.10 墨尔本大学 医学院 细胞信号通路/免疫学 哲学博士

2005.08-2010.06 东南大学 公共卫生学院 预防医学专业 医学学士

研究方向

基于铁基纳米材料的心血管免疫调控：针对血管疾病的降脂及抗炎疫苗开发；血管早期炎症的免疫调控；基于铁基纳米颗粒的动脉粥样硬化靶向药物。

磁性纳米材料的免疫调控机制及应用：铁基纳米材料运用于免疫细胞的体内命运动态示踪；铁基纳米材料影响DC、巨噬等免疫细胞定向分化的功能及调控机制研究。

科研项目

国家自然科学基金青年项目，32301189,主持

(PCSK9/ApoB-100双靶向动脉粥样硬化磁性纳米脂质体疫苗的构建及应用)

江苏省自然科学基金青年项目,BK20220824，主持

(双靶向递送纳米脂质体肿瘤疫苗的制备及应用)

江苏省双创博士,JSSCBS20210107,主持

(磁性纳米材料应用于树突状细胞（DC)疫苗的示踪研究)

科技部重点研发计划子课题，2021YFA1201403，参与

(新型磁性微纳器件及磁场遥控系统研发)

学术论文

(1)JingyiSheng^#*, Yang Liu^#, Ding He, Lingyuan Wu, Lan Liu, Guangxiang Si, Yan Shen, Fang Yang*, Ning Gu*, Magnetic delivery of antigen-loaded magnetic liposomes for active lymph node targeting and enhanced anti-tumour immunity,Advanced Healthcare Materials, 2023, 2301232. https://doi.org/10.1002/adhm.202301232

(2)Jingyi Sheng, Yuehuang Wu, He Ding, Kaizheng Feng, Yan Shen, Yu Zhang*, Ning Gu*, Multienzyme-like Nanozymes: Regulation, Rational Design, and Application,Advanced Materials, 2023, doi.org/10.1002/adma.202211210

(3)Chu Shi,Jingyi Sheng*, Guangxiang Si, Yan Li, Yan Shen, Ning Gu*, Spy chemistry enables stable protein immobilization on iron oxide nanoparticles with enhanced magnetic properties,Journal of Materials Science&Techonology, 2023,10(161),161-169.(IF:10.32)

(4)Dewen Ye, Mingxi Li, Kaizheng Feng,Yu Zhang,Jingyi Sheng*, Ning Gu*, Long-term fate tracking and quantitative analyzing of nanoparticles in stem cells with bright-field microscopy,Nano Today, 2022, 44: 101506-101506

(5)HeDing,YuxinZhang,Yu Mao, Yan Li, Yan Shen,Jingyi Sheng*, Ning Gu*, Modulation of macrophage polarization by iron-based nanoparticles,Medical Review, 2023, doi.org/10.1515/mr-2023-0002

(6)Jingyi Sheng^#, Li Wang^#, Patrick Ming-Kuen Tang^#, Hong-Lian Wang,Jian-Chun Li, Bi-Hua Xu, Vivian Weiwen Xue, Rui-Zhi Tan, Nana Jin, Ting-Fung Chan, Xiao-Ru Huang, Ronald CW Ma, Hui-Yao Lan*,Smad3 deficiency promotes beta cell proliferation and function indb/dbmiceviarestoring Pax6 expression,Theranostics, 2021, 11(6): 2845-2859.

(7)JingyiSheng, Chu Shi and Ning Gu*, Clinical trials of MRI-based immune cell imaging: challenges and perspectives,Science Bulletin, 2021,66(4):303-306

(8)Jian Zhang^#,Jingyi Sheng^#,Liwei Dong, Yinli Xu, Liming Yu, Yu Liu, Xiaoru Huang, Song Wan, Hui-Yao Lan*, Huishan Wang*, Cardiomyocyte-specific loss of RNA polymerase IIsubunit 5-mediating protein causesmyocardialdysfunction and heart failure,Cardiovascular Research, 2019,115(11):1617-1628