玄武岩纤维作为增强体用于硬组织修复材料的研究

本文首次将玄武岩纤维作为增强体用于硬组织修复材料。利用玄武岩纤维强度高、韧性好等优异的力学性能，将其与PLA基体复合，设计制备了新型BF/PLA复合材料，并对复合材料微观结构、力学性能、生物相容性进行了研究。

Xi Chen, Yan Li and Ning Gu,A novel basalt fiber-reinforced polylactic acid composite for hard tissue repair,Biomed. Mater. 5 (2010) 044104

Figure 1. SEM photographs of the neat PLLA scaffold: (a) cross section, (b) vertical section and (c) outer surface, as well as the porous BF/PLLA scaffold with 15 wt% BF content: (d) cross section, (e) vertical section and (f ) outer surface.

Figure 2. Dependence of the compressive modulus and compressive strength on the fiber content in the composites. Data represent the mean ± SD, n = 5.

Figure 8. Morphology evaluation of osteoblasts on the BF/PLLA films (a), (b), (c) and (d) and the PLLA films (e), (f ), (g) and (h) by fluorescence microscopy: most cells were adherent to their substrates after 1 day: (a) and (e); cells enlarged and entered the splitting phase after 3 days: (b) and (f ); 5 days later they were fully spread (c) and (g), with cell sizes ranging from 50 to 70 μm in diameter; and 7 days later cells grew up to the formation of a complete monolayer (d) and (h) (scale bar = 50 μm).